UA SBRP Student Sarah Buffington Receives Award at the 2007 Mountain West Society of Toxicology Meeting

UA SBRP student, Sarah Buffington, (advisor, A. Jay Gandolfi) received a third place award for her poster entitled, “Chronic Exposure to Monomethylarsonous Acid Induces Changes in Human UROtsa Cells Consistent with Urothelial Tumorigenesis” in the student poster competition at the 2007 Mountain West Society of Toxicology Meeting, September 6-7, 2007 in Breckenridge, Colorado.

Mrs. Buffington’s research characterizes the spectrum of changes that occur as a result of chronic monomethylarsonous acid (MMA(III)) treatment as it relates to known characteristics of bladder carcinogenesis. Her ongoing laboratory studies indicate that chronic exposure to MMA(III), models the development of urothelial tumorigenesis, showing characteristics of non-invasive papillary tumors in the early months of MMA(III) treatment and later advancing to the invasive high-grade stage with prolonged exposure beyond 5 months of treatment.

Please join the UA SBRP in congratulating Sarah Buffington.